Klaus Tenbrock Selected Research

Arthritis (Polyarthritis)

9/2023	Treat-to-target strategies for the management of familial Mediterranean Fever in children.
12/2022	Outcome of adult patients with JIA treated with the biosimilar Benepali®: results of the biologic register JuMBO.
6/2018	The transcription factor CREM drives an inflammatory phenotype of T cells in oligoarticular juvenile idiopathic arthritis.
1/2018	Transcription factor motif enrichment in whole transcriptome analysis identifies STAT4 and BCL6 as the most prominent binding motif in systemic juvenile idiopathic arthritis.
12/2015	No association of IL-12p40 pro1.1 polymorphism with juvenile idiopathic arthritis.
5/2015	Efficacy and safety of etanercept in patients with the enthesitis-related arthritis category of juvenile idiopathic arthritis: results from a phase III randomized, double-blind study.

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Klaus Tenbrock Research Topics

Disease

17	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2022 - 10/2002
10	Inflammation (Inflammations) 09/2023 - 01/2011
9	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 12/2022 - 02/2014
6	Arthritis (Polyarthritis) 09/2023 - 05/2015
4	Asthma (Bronchial Asthma) 10/2023 - 11/2015
4	Hypersensitivity (Allergy) 12/2018 - 03/2007
3	Autoimmune Diseases (Autoimmune Disease) 08/2014 - 11/2002
2	Respiratory Hypersensitivity 10/2023 - 11/2015
2	Colitis 01/2023 - 01/2016
2	Body Weight (Weight, Body) 01/2023 - 11/2018
2	Hepatitis 01/2021 - 03/2015
2	Infections 01/2020 - 01/2018
2	Hypoxia (Hypoxemia) 03/2007 - 04/2003
1	Niemann-Pick Diseases (Niemann Pick Disease) 10/2023
1	Thalassemia 01/2023
1	Ulcerative Colitis 01/2023
1	Pain (Aches) 12/2022
1	Anorexia Nervosa 01/2022
1	Hypertension (High Blood Pressure) 01/2022
1	Proteinuria 01/2022
1	Alveolar capillary dysplasia 06/2021
1	Pulmonary Arterial Hypertension 06/2021
1	Cutaneous Lupus Erythematosus 01/2021
1	Macrophage Activation Syndrome 01/2020
1	Neonatal Sepsis 01/2020
1	Cytopenia 01/2020
1	Rheumatic Diseases (Rheumatism) 01/2019
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2019
1	Congenital Plasminogen Deficiency 01/2019
1	Drug Hypersensitivity (Drug Allergy) 12/2018
1	Experimental Arthritis 06/2018
1	Neoplasms (Cancer) 01/2018
1	Stroke (Strokes) 04/2017
1	Liver Diseases (Liver Disease) 01/2017
1	Demyelinating Diseases (Demyelinating Disease) 03/2016
1	Negative rheumatoid factor polyarthritis 12/2015

Drug/Important Bio-Agent (IBA)

10	CytokinesIBA 01/2022 - 01/2011
5	Proteins (Proteins, Gene)FDA Link 01/2019 - 10/2002
5	Cyclic AMP Response Element ModulatorIBA 01/2017 - 12/2011
5	Interleukin-2 (IL2)IBA 04/2005 - 10/2002
3	Etanercept (Enbrel)FDA Link 12/2022 - 05/2015
3	Interleukin-6 (Interleukin 6)IBA 01/2022 - 02/2014
3	Transcription Factors (Transcription Factor)IBA 06/2018 - 03/2015
2	AcidsIBA 10/2023 - 01/2020
2	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 10/2023 - 01/2020
2	AntibodiesIBA 10/2023 - 01/2022
2	GlucocorticoidsIBA 10/2023 - 08/2014
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2022 - 06/2015
2	Interleukin-1 (Interleukin 1)IBA 03/2021 - 01/2020
2	Concanavalin AIBA 01/2021 - 03/2015
2	OvalbuminIBA 01/2020 - 06/2018
2	SteroidsIBA 01/2020 - 12/2008
2	Toll-Like Receptor 4IBA 01/2019 - 09/2007
2	AllergensIBA 01/2017 - 03/2007
2	Interleukin-17 (Interleukin 17)IBA 01/2017 - 12/2011
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 09/2011 - 09/2004
2	zeta chain antigen T cell receptor (TCR zeta chain)IBA 11/2005 - 11/2002
2	Adenosine (Adenocard)FDA LinkGeneric 09/2004 - 10/2002
1	Antidepressive Agents (Antidepressants)IBA 10/2023
1	Cholinergic Antagonists (Anticholinergics)IBA 10/2023
1	Sympathomimetics (Sympathomimetic Amines)IBA 10/2023
1	SphingolipidsIBA 10/2023
1	Acetylcholine (Acetylcholine Chloride)FDA Link 10/2023
1	Amitriptyline (Elavil)FDA LinkGeneric 10/2023
1	EnzymesIBA 10/2023
1	Colchicine FDA LinkGeneric 09/2023
1	Sickle HemoglobinIBA 01/2023
1	tofacitinibIBA 01/2023
1	Janus Kinase InhibitorsIBA 01/2023
1	Biosimilar PharmaceuticalsIBA 12/2022
1	ametantrone (HAQ)IBA 12/2022
1	MicroRNAs (MicroRNA)IBA 01/2022
1	Oxygen (Dioxygen)IBA 06/2021
1	Leucine (L-Leucine)FDA Link 04/2021
1	LigandsIBA 01/2021
1	Cell Adhesion MoleculesIBA 01/2021
1	Cell Adhesion Molecule-1IBA 01/2021
1	IntegrinsIBA 01/2021
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2020
1	canakinumab FDA Link 01/2020
1	tocilizumab (atlizumab)FDA Link 01/2020
1	AlarminsIBA 01/2019
1	Antirheumatic Agents (DMARD)IBA 01/2019
1	CalciumIBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	Methotrexate (Mexate)FDA LinkGeneric 01/2019
1	PlasminogenIBA 01/2019
1	Pattern Recognition ReceptorsIBA 01/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2018
1	InterleukinsIBA 01/2018
1	Adenosine DeaminaseIBA 04/2017
1	Immunoglobulin E (IgE)IBA 01/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2016
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2016
1	interleukin-21 (interleukin 21)IBA 01/2016
1	Dextrans (Dextran)FDA Link 01/2016
1	Interleukin-12 Subunit p40IBA 12/2015

Therapy/Procedure

9	Therapeutics 10/2023 - 08/2014
1	Artificial Respiration (Mechanical Ventilation) 06/2021
1	Biological Therapy 01/2020